A*STAR - Agency For Science, Technology And Research Hiring! Full Time Scientist, Laboratory of Precision Disease Therapeutics (GIS) in - Ricebowl

Position Overview

The Laboratory of Precision Disease Therapeutics focuses on therapeutic target discovery and translational development for metabolic dysfunction-associated steatotic hepatitis (MASH), with a strong emphasis on siRNA-based therapeutics.

Our research integrates patient-derived multi-omics datasets with in vivo functional genetic screening and human in vitro disease models to systematically identify and validate clinically relevant therapeutic targets.

We are seeking a highly motivated Postdoctoral Fellow to lead and contribute to projects involving therapeutic target validation, disease modeling, and translational therapeutic development.

The successful candidate will work in a highly interdisciplinary and translational research environment and is expected to contribute scientifically through experimental design, data interpretation, troubleshooting, and project development.

Requirements

• Design and execute independent research projects related to MASH and siRNA therapeutics
• Perform molecular and cellular biology experiments, including gene perturbation studies and disease modeling
• Contribute to in vivo studies and functional validation experiments
• Analyze and interpret experimental data and present findings in internal and external meetings
• Participate in manuscript preparation, grant applications, and collaborative projects
• Contribute to scientific discussions, troubleshooting, and project strategy development
• Mentor junior lab members when appropriate
  
  

Requirements

• PhD degree in Biomedical Sciences, Molecular Biology, Pharmacology, or related fields
• Strong background in molecular biology, cell biology, or translational disease research
• Experience with mammalian primary cell culture and molecular techniques
• Ability to independently plan and execute experiments
• Strong scientific reasoning, communication, and problem-solving skills
• Ability to work collaboratively in a fast-paced research environment
  
  

Preferred Qualifications (Not Required But Advantageous)

• Experience in liver disease, metabolic disease, or fibrosis research
• Experience with siRNA or gene knockdown approaches
• Experience with in vivo mouse studies
• Familiarity with histology or imaging-based assays
• Experience working in translational or interdisciplinary research settings
• Publication record in relevant research areas
  
  

Interested Candidates Are Invited To Send a Cover Letter Stating Your Research Interests And Experience, Curriculum Vitae, And The Names And Email Addresses Of Three References To:

LEE Yong-An (*************)